How to recharge for youth? University of London: Stealing other people's telomeres can increase life expectancy by 30 times

Since ancient times, people's pursuit of health and longevity has never stopped. Dating back to the Qin Dynasty, in his later years, in order to achieve immortality, Qin Shihuang sent people to find celebrities from all over the world to make "elixir", and even paid tribute to nearly a thousand virgins and virgins. From 35 years old before World War II to 78.2 years old today.

Previously, Bank of America Merrill Lynch, a well-known investment bank in the United States, predicted that with the development of modern science and technology, the healthy lifespan of human beings is expected to exceed 100 years. Now, an experiment in "Nature" about cells "robbing" other people's telomeres, which can magnify the effect of life extension by nearly 30 times, has even broadened the possibility of achieving a hundred years for all people.

01 Star-attracting Dafa reappears? Stealing other people's telomeres can prolong life 30 times

In mid-September, Alessio Lanna's research team at the University of London found in experiments that the telomeres "robbed" by T cells from other types of cells or individuals can significantly slow down the aging process, and the life extension effect can reach up to 30 times. The experimental results were also published in the authoritative journal "Nature".

As the "life clock" of the cell, telomeres are "cap-shaped" structures that exist at the ends of the cell's chromosomes. When cells undergo mitosis, telomeres ensure the integrity of the genetic material. As the number of divisions increases, the length of the telomere will also shorten, and when it is exhausted, the life activities of the cell will also stop. Therefore, telomere length is also regarded as a major criterion for measuring the length of life.

As one of the "main forces" of immune cells, T cells play an important role in maintaining a healthy lifespan. In this experiment, the researchers found that T cells "rob" the telomeres carried by antigen-presenting cells (APCs) when they are in an immune state, thereby achieving large-scale lifespan extension. Compared with self-reliance, this method of "grabbing" others can amplify the life extension effect of cells by about 30 times.

It is worth noting that the exchange within the same individual is tantamount to "removing the east wall to make up for the west wall", and there will always be a time when it runs out. In this regard, the research team tried to "rob" some telomeres from other individuals (human blood/mice) through artificial means, and the results proved that this "robbing" can still be carried out across species .

02 Telomere has become a "potential stock" for life extension, and mature technologies have emerged

Professor Alessio Lanna, the leader of the research team, said that this experiment confirmed that only by transferring telomeres between cells, the speed of aging can be changed , which will open up a new direction for extending telomeres and slowing down aging. However, some scholars still have reservations about this. They believe that this mechanism has only been verified in human cells and mice in vitro, and whether it can be realized clinically in the future needs further verification.

At present, the relatively mature "telomere extension" technology is derived from a "ruohui" technology from Harvard Medical Center in the United States. At first, Professor David, the director of the medical center, carried out relevant animal experiments and found that this type of technology played a positive role in improving key physiological indicators such as muscle endurance, agility and bone density.

Last year, the Chinese Academy of Sciences carried out further clinical trials on the "Ruohui" technology, and the results proved that after three months of exposure to this technology, the telomere length in the cells increased by 1-2 times, which is equivalent to physiologically. About 5 years younger.

Confined to the technical fortress, this type of technology was originally only circulated in the United States and Japan, and the market was even marked with a high price of about 21,000 grams. With the development of domestic biotechnology, the Chinese bio-enterprise Geneharbor broke through the technical shackles and developed a bio-enzyme method that reduced the cost of such technology by 95%. The similar technology "Ruohui" was also able to settle in JD.com in four figures. This year's Double 11 sold thousands The sales volume of 10,000 products ranks first in its sub-category list, becoming a young black technology accessible to ordinary people.

03 Is the per capita age of 100 no longer a "idiot's dream"?

With the development of modern technology, using technology to achieve longevity is no longer just a prospect. Last year, Israeli scientists found that sixty-year-olds who received "hyperbaric oxygen therapy" for three months returned to a young state in their 20s in many physiological indicators; and this year, the National Institute of Health of the United States discovered a kind of gingerene in ginger. Ketone A substance can remove nearly 50% of aging human fibroblasts within 2 days.

Perhaps, as stated in the book "A Centenary Life", with the advancement of science and technology, it has become an inevitable trend for all people to live a hundred years old. We should all think about how to meet this era when everyone is a hundred years old in the future.