Do people get old instantly? Scientists collect blood from 4,000 people and find that after the age of 34, they will become more and more ugly

In our inherent cognition, we always think that life goes by day by day, and that people are getting old slowly. In fact, this is not the case.

Writer Haruki Murakami once said, " People grow old in an instant." As they grow older, many people also begin to find that when they pass a certain age, even if they have paid great attention to their maintenance, their whole body will still remain intact. It still looks like a deflated ball, and various small problems occur frequently in the body. The claim that aging will accelerate after reaching a certain age is actually scientifically based.

A research team from Stanford University in the United States conducted a similar analysis of the plasma protein trajectories of more than 4,000 volunteers aged 18-95, and then concluded that people will indeed experience three waves of obvious aging thresholds in their lifetime, 34 years old, 60 and 78 years old. Why are these three time points, and where does this conclusion come from?

The aging of the body is not uniform, 34, 60, 78 will accelerate the "breakdown"

As early as 2014, researchers at the University of California made a surprising discovery. After replacing the blood of young mice with the blood of old mice, the old mice quickly regained tissue vitality and the signs of aging were significantly reversed. . After several studies, it was confirmed that young blood is the source of rejuvenation in mice.

Or inspired by this, in 2019, a research team from Stanford University in the United States once again conducted an in-depth exploration of the relationship between the body's plasma proteins and aging. They collected a variety of plasma protein levels of 4,236 volunteers with age distributions in the juvenile, middle-aged, and elderly. When using a linear model for specific analysis, they revealed their underlying laws.

The research team found that the 34-year-old volunteers had a significant reduction in the content of proteins that support structures such as collagen, and the feedback on the face was skin sagging, loss of elasticity and luster.

For volunteers in the 60 and 78 age groups, their aging was mainly reflected in their health. In this data, cardiovascular disease is the most frequent occurrence among people over 60 years old, which is due to significant changes in hormone activity, binding function and blood pathway-related proteins in the body; while at 78 years old, it is mainly due to blood pathway, bone morphology The signal transduction-related proteins undergo dramatic changes, which makes them highly susceptible to various aging-related diseases such as Alzheimer's disease.

Some people may ask, why are these three age points so special, and what causes this cliff-like aging?

Quantitative changes in gene mutations lead to qualitative changes

The reason for the cliff-like aging at these three time points can also be traced back to hematopoietic stem cells. The University of Cambridge analyzed the hematopoietic stem cells of 10 volunteers aged 0-81 and sequenced their whole genomes, and concluded that these hematopoietic stem cells developed 17 point mutations each year, and the length of the telomere was also different. There will be a loss of 30 base pairs. At a young age, because there are many hematopoietic stem cells in the human body, the micro-reduction feedback to the body is facial aging that is harmless to health.

When entering the 70-year-old age, the population of hematopoietic stem cells will undergo significant changes, and this is what we often say: quantitative changes cause qualitative changes, and the body will show a cliff-like aging.

Today, with the booming development of the biotechnology field, scientists have naturally explored some powerful interventions. Just like the "Wlife" substance discovered by the Harvard Biosciences team in 2017, it is a special factor that can promote the repair of cells in the body. We all know that telomeres are an important symbol of cell aging. Once they can no longer divide, it means death. .

However, as a "youth factor", this substance is also inextricably linked with telomeres. The study pointed out that after ingesting this substance, the telomeres in the body of old mice not only doubled, but also the mitochondrial mass was increased. In the end, the mice also successfully reversed various aging indicators in the body, and lived more than 1,000 days.

In addition, the experimental results of the University of Tokyo showed that the "Wlife" substance was also found to be able to directionally activate signals related to longevity such as DNA repair, thereby delaying the arrival of these three aging nodes.

With the advent of these scientific research results one by one, the people who were the first to get the gossip also successively took the finished product "Wlife" into their pockets on JD. , and from the feedback behind the platform data, it can be seen that more and more people are willing to pay for health.

With the blessing of biotechnology, everyone is expected to cross the century-old era

Analysts from Wall Street Bank of America Merrill Lynch once gave such a report that by 2020, medical knowledge will double every 73 days, and these medicines can also further prolong the lifespan of the body. I believe that in the future, with the help of technology Now, everyone is also expected to cross the century-old era.

In fact, we are also moving in this direction today. The "Wlife" substance discovered by researchers has confirmed the previous prediction. Although the current population's aging pressure is increasing, it is precisely because of pressure. We believe that with the support of modern technology, we will also have the confidence to resist aging and welcome a healthy and fulfilling old age.