Shanghai launches inhaled COVID-19 vaccination, what are its advantages? What should I pay attention to when using it?

On September 4, 2022, the world's first "COVID-19 vaccine for inhalation" was urgently approved for marketing in China. This is a recombinant novel coronavirus vaccine (type 5 adenovirus vector), which has been approved by the State Drug Administration and can be used as a booster for emergency use.

On October 26, 2022, Shanghai will use the inhaled COVID-19 vaccine as a full-time inoculation of "Kexing", "Beijing Bio", "Wuhan Bio", "Connox" and other COVID-19 vaccines for 6 months. One of the booster immunization options for adults and is free of charge.

Two Advantages of "Inhaled COVID-19 Vaccine"

There are already a number of COVID-19 vaccines. Why should inhaled COVID-19 vaccines be approved for marketing? What are the advantages of inhaled vaccines?

The first major advantage: The obvious advantage is that there is no need for injections, the fear of injections, the pain caused by needles, and the pain of arm muscles after injections naturally no longer exist.

The second major advantage: Secondly, the COVID-19 vaccine for inhalation reaches the lung tissue through oral breathing through inhalation, and stimulates the triple immunity of mucosal, humoral and cellular. The oral cavity and respiratory mucosa are the main routes of transmission of the COVID-19 virus. Strengthening the immunity of the respiratory mucosa can help prevent the infection of the COVID-19 virus. The above two points can be summed up as follows: "COVID-19 vaccine for inhalation" has stronger anti-infection ability and fewer side effects.

What to watch out for when using the "COVID-19 vaccine for inhalation"

Shanghai residents can now register online for booster immunization with inhaled COVID-19 vaccine.

Before making an appointment, it is still necessary to determine whether you are eligible for the "COVID-19 vaccine for inhalation". First, the "COVID-19 vaccine for inhalation" is currently only approved for use by adults over the age of 18, and children cannot currently use inhaled preparations. Secondly, it is used as a booster shot, which means that the full immunization of the COVID-19 vaccine has been completed before and it has been 6 months. Finally, according to the relevant requirements of the state, only one booster shot needs to be added after the whole vaccination is completed, so people who have already received one booster shot do not need to boost the immunization.

It should be reminded that the vaccination of recombinant COVID-19 virus vaccine for inhalation has the following contraindications: (1) Those who are allergic to the active ingredients in this product, any inactive ingredients, or substances used in the production process, or those who have previously vaccinated the same kind Allergic to the vaccine. (2) Those who have experienced severe allergic reactions to vaccines in the past (such as acute allergic reactions, angioedema, dyspnea, etc.). (3) Those with uncontrolled epilepsy and other progressive neurological diseases, and those with a history of Guillain-Barre syndrome. (4) Those who are febrile, or suffering from acute diseases, or acute exacerbations of chronic diseases, or patients with uncontrolled severe chronic diseases; (5) Pregnant women.

Probably the vast majority of people have not used inhaled vaccines, so it is necessary to learn how to inhale vaccines before vaccination. The inhaled vaccine looks like a milk tea cup with a mouthpiece at the front and a white aerosol in the cup. First, let's take a deep breath, and pay attention to avoid the suction mouth when exhaling.

The second step is to hold the nozzle of the atomizing cup in your mouth, and take a deep breath until there is no fog in the cup. Hold your breath for more than 5 seconds, then breathe normally to complete the vaccination. If there is still a clear white aerosol in the cup after inhaling, it means that the inhalation has failed and you need to inhale another dose. If after inhalation, you choked due to excessive force, throat discomfort, or did not hold your breath for 5 seconds due to unfamiliar operation, you still need to inhale another dose. Of course, at most one repeated puff is allowed.

Finally, many people are concerned about whether the inhaled vaccine will cause a positive nucleic acid test. Since the vaccinated vaccine does not contain the detection gene locus for nucleic acid detection, it will not cause nucleic acid positive.