Life lengthened by 28%? Portuguese scientists discover 'reverse growth switch' to reverse aging
There are eight sufferings in human beings: "birth, old age, sickness, death, parting from love, resentment and hatred, not getting what you want, and the five Yins are flaming." The world created us so that we can enjoy everything that life brings us, and we cannot escape birth, old age, sickness and death under the laws of nature. But looking back at the long history, you will find that human beings have never given up their pursuit of "immortality".
In ancient Chinese history, there were as many as a dozen emperors who died early because of taking the so-called "longevity elixir". This shows how strong human yearning for longevity is, and this strong pursuit has intensified along with the rapid development of modern science and technology.
FOXM1 Stretches 28% Life Cycle
There has been a wave of research in the relevant academic circles, hoping to find a way to slow down the speed of human aging. Moreover, there are many related research results, and various inverse growth technologies have been discovered one after another. Recently, the research team of the University of Porto in Portugal has discovered an effective anti-aging method - the transcription factor FOXM1, which can not only prolong the life cycle of mice by 28%, but also improve many physiological functions of mice. The research results were published in the world-renowned journal "Nature".
The research team stated that after analyzing a large number of previous related studies, they found that the transcription factor FOXM1 plays a major role in the process of human skin fibroblasts turning to aging. Therefore, the research team wondered whether this transcription factor could be removed from the cells, so as to slow down the aging rate of cells, so as to increase the survival period of animals.
Around this theory, the research team carried out relevant animal experiments, and in order to observe the changes brought about by the withdrawal of FOXM1 in a shorter period of time, they deliberately selected mice with progeria (HGPS: a serious premature aging disease) mice were compared with normal mice. After several stages of the FOXM1 withdrawal experiment, the physiological indicators of progeria mice showed significant improvement.
The skin, fat, aorta, bone and other body aging indicators of mice with progeria have improved to varying degrees. At the same time, in the experiment of the normal mice group, important aging indicators such as subcutaneous fat, muscle fibers, and aorta of the normal mice also showed significant reversal, and the median life span and maximum life span of the normal mice were prolonged by 28% and 29%, respectively. %, and also slowed down the rate of weight loss associated with aging!
There are already successful precedents in academia
Shortly after the publication of the research results, many people in the academic circle expressed their approval, thinking that the research results may become a new method for the treatment of progeria and natural aging in the future. The reason why the academic community is very optimistic about this is that there have been successful examples before. For example, according to data feedback from relevant international platforms such as JD.com, the "WLife" aging intervention technology discovered by Harvard biology professor David in 9 years has always been at the forefront of the list of similar products.
At the beginning of the discovery of this substance, many world-renowned biological institutions, including Qingbei, Kyoto University, and Mayo Research Institute, conducted in-depth analysis of the effects of "WLife" substances, and it was supplemented by exogenous sources. The aging mice on the substance not only showed reverse growth changes, but also showed younger changes in indicators closely related to aging, such as hair, speed, and muscle strength.
It is also thanks to the appearance of this substance that Professor David, who discovered it, was selected by the journal "Nature" as one of the 100 people who have influenced the world. At the same time, as the effect of this kind of substance has been confirmed, capital from all sides has also focused on this technology, believing that there are infinite possibilities behind it. , and have become pro-testers of this substance, after all, who doesn't want to live a few more years.
With the injection of multi-party capital, this kind of substance was quickly realized, but the technical limitation at that time was that the cost of this kind of technology was frighteningly high. One gram was once sold for a sky-high price of 200,000, so it could only become the favorite of a few rich people. Exclusive. Even with the efforts of the biotechnology company Wright Health, this kind of substance entered JD.com and other related international trading platforms together with other cutting-edge technologies, and the cost dropped to four digits, which is still not affordable by the general population.
Although compared with this kind of aging intervention technology, there are still many deficiencies in the experiments related to the transcription factor FOXM1, but FOXM1 can deal with the effect of pathological aging, which is also unprecedented in other similar technologies, which means that if future research on The research on FOXM1 can also be further substantiated, so FOXM1 will also have a place in the field of biological intervention in aging in the future.
There is an old saying that one stands at 30, which means that only after the age of 30 can one be fully independent and mature, and there can be several thirty years in one's life. What's more, after the age of 30, we will spend at least 20 years to raise our next generation, so 50 years will be gone. It can only be said that human life is too short, and many people still have many unfulfilled wishes after passing away. Perhaps this is the reason why human beings are obsessed with pursuing a longer life span!