28% longer life? Portuguese scientists discover 'reverse growth switch' that turns aging into reality
People have eight sufferings: "birth, old age, sickness, death, separation from love, meeting of hatred and hatred, not being able to seek, and the five yin blazing." The world has created us so that we can enjoy everything that life brings to us, and we cannot escape the natural laws of birth, aging, sickness and death. But looking back at the long history, you will find that human beings have never given up the pursuit of "eternal life".
In ancient Chinese history, as many as a dozen emperors died prematurely because of taking the so-called "longevity medicine". It can be seen how strong human beings yearn for longevity, and this strong pursuit is also intensified with the rapid development of modern science and technology.
FOXM1 stretches 28% life cycle
Related academic circles set off a wave of research, hoping to find a way to slow down the speed of human aging. And there are not a few related research results, and various reverse growth techniques have been discovered one after another. Recently, a research team from the University of Porto in Portugal discovered an effective anti-aging method, the transcription factor FOXM1, which can not only prolong the life cycle of mice by 28%, but also improve many physiological functions of mice. The research results were published in the world-renowned journal "Nature".
The research team said that after analyzing a large number of previous related studies, they found that the transcription factor FOXM1 plays a major role in the process of human skin fibroblasts turning to aging. Therefore, the research team wondered whether this transcription factor could be removed from cells to slow down the rate of cell aging, thereby increasing the survival cycle of animals.
Around this theory, the research team carried out relevant animal experiments, and in order to observe the changes brought about by the removal of FOXM1 in a shorter period of time, they deliberately selected patients with progeria (HGPS: is a serious disease). of premature aging) mice were compared with normal mice. After several stages of withdrawal of FOXM1, mice with progeria showed marked improvements in their physiology.
The skin, fat, aorta, bone and other body aging indicators of the progeria mice have improved to varying degrees. At the same time, in the experiment of the normal mouse group, the subcutaneous fat, muscle fibers, aorta and other important aging indicators of normal mice also showed a significant reversal, and the median lifespan and maximum lifespan of normal mice were lengthened by 28% and 29% %, in addition to slowing down the rate of weight loss associated with aging!
Academia has a long history of success
Shortly after the publication of the research results, many people in the academic community expressed their approval, believing that this research result may become a new method for the treatment of progeria and natural aging in the future. The academic community is very optimistic about this because there have been successful examples before. For example, according to the data feedback from relevant international platforms such as JD.com, the "WLife" intervention aging technology discovered by Harvard biology professor David in 9 years has always been at the forefront of the list of similar products.
At the beginning of the discovery of this substance, many world-renowned biological institutions including Qingbei, Kyoto University, and the Mayo Institute conducted in-depth analysis of the effects of "WLife" substances, and were supplemented by exogenous substances. The old-aged mice not only showed changes in inverse growth, but at the same time, indicators closely related to aging, such as hair, speed, and muscle strength, all showed changes in youth.
It is also thanks to the emergence of this substance that Professor David who discovered it was selected as one of the 100 people who influenced the world by the journal Nature. At the same time, as the effects of such substances have been confirmed, various capitals have also set their sights on this technology, believing that there are infinite possibilities behind it. Even Buffett, Bezos, Li Ka-shing and others not only enter the market to invest in the transformation of the results of such substances , and have also become the pro-testers of the substance, after all, who doesn't want to live a few more years.
With the injection of multi-party capital, this kind of material was quickly turned into fruit, but the technical limitation at that time was that the cost of this technology was terrifyingly high. One gram was sold for a sky-high price of 200,000, so it could only become a wealthy few. Exclusive. Even after the efforts of the biotechnology company Lightweijian, such substances and other cutting-edge technologies entered related international trade platforms such as JD.com, and the cost dropped to four digits, which is still not affordable for the general population.
Although compared with this type of interventional aging technology, there are still many deficiencies in the related experiments of transcription factor FOXM1, but FOXM1 can deal with the effect of pathological aging, which is also not possessed by other similar technologies. The research of FOXM1 can also be further substantiated, so FOXM1 will also have a place in the field of biological intervention in aging in the future.
The old saying stands at 30, which means that you can be fully autonomous and mature after the age of 30, and life can have several thirty years. What's more, after the age of 30, we have to spend at least 20 years to raise our next generation, so 50 years are gone. It can only be said that human life is too short, and many people still have many unfulfilled wishes after death. Perhaps this is the reason why human beings are obsessed with the pursuit of longer life!