How to choose from many types of metformin? Teach you 3 tricks, so taking medicine to lower blood sugar is safer and more efficient

Metformin, as the "big brother" in the field of hypoglycemic drugs, plays an irreplaceable role in the treatment of type 2 diabetes. As a basic drug for diabetes treatment, metformin can help diabetics who cannot control blood sugar through simple diet and exercise, control blood sugar, and at the same time can be combined with insulin, sulfonylurea hypoglycemic drugs and other drugs for treatment, and the hypoglycemic effect is more obvious.

As such a commonly used drug, people with diabetes often need to be more cautious in their selection. The effects of drugs in different doses and dosage forms are also different. For most people with diabetes, they need to take medicine for life. The rationality of the price is also when people with diabetes choose drugs. An important point to consider.

So how to choose metformin, which is safer and more efficient for hypoglycemic? 3 points to note:

Ordinary type, enteric-coated type, slow-release type, the choice is good

There are three types of metformin preparations, including ordinary type, enteric-coated type, and sustained-release type, which are presented as tablets and capsules. Which of these types has better therapeutic effect, what is the difference, and how to choose?

According to the release position, metformin ordinary tablets or capsules are mainly released in the stomach after taking, enteric-coated tablets are mainly released in the intestinal tract, and sustained-release tablets and sustained-release capsules are released and dissolved in the gastrointestinal tract at the same time.

According to the reaction time, enteric-coated and sustained-release preparations have a higher degree of absorption and faster absorption than ordinary tablets and capsules. In addition, in terms of absorption, we have to mention the side effects. Ordinary tablets are released in the stomach, so it may cause stomach discomfort, which is not very friendly to patients with gastrointestinal diseases. The other two types are released in the intestine, and the side effects are not obvious.

Therefore, tablets and capsules are not the focus of selection, but the selection of formulation types. You can choose according to your own situation, mainly considering absorption and drug side effects, and other aspects have little impact.

0.25g, 0.5g, 0.85g, which one is more cost-effective

Metformin is generally divided into three categories according to the dose: 0.25 grams, 0.5 grams, and 0.85 grams. The size of the selected dose is related to the patient's blood sugar and complications. The basic principle of use is "take a small dose at the beginning and gradually increase the dose". Generally, it is advisable to take 500 mg per day at the beginning, and gradually increase the amount after 1-2 weeks of taking, and the maximum cannot exceed 2000 mg.

The initial small dose can choose 0.25 grams and 0.5 grams of drugs, in order to maintain the blood concentration, take the drug 2 or 3 times a day. After gradually increasing the amount, it can be changed to 0.5 or 0.85 grams of the drug, which can be taken 1-2 times a day. In addition, the side effects and complications of the patients also need to be considered. For patients with underweight and obvious gastrointestinal side effects, it is recommended to take small doses of drugs multiple times, which can slow down the reaction of drug side effects. For overweight patients with cardiovascular diseases such as hypertension and hyperlipidemia, it is better to choose large doses of drugs, which are more conducive to maintaining blood drug concentrations, stabilizing blood sugar, and reducing the incidence of cardiovascular complications.

Stomach hurt? Liver and kidney damage? Safer and more effective

As we all know, after taking metformin, a small number of patients will experience gastrointestinal discomfort, but generally after taking it for a period of time, the tolerance will be enhanced, and most of the patients' nausea, vomiting and other symptoms will alleviate or disappear. In addition to this side effect, a question that everyone is paying more attention to recently about the side effects of metformin is whether it will damage the liver and kidneys?

The first thing to clarify for metformin is that it has no hepatotoxicity or nephrotoxicity, and long-term use will not damage liver and kidney function. Secondly, it is not recommended for patients with hepatic and renal insufficiency, mainly due to the consideration of side effects. Patients with hepatic and renal insufficiency have poorer metabolism and detoxification ability than ordinary people. Therefore, after taking metformin, the gastrointestinal discomfort will be more severe, severe vomiting, Nausea and diarrhea will aggravate the damage to liver and kidney function, which is not conducive to the treatment of liver disease and kidney disease.

On the other hand, long-term use of metformin will increase the situation of lactic acidosis, and also increase the metabolic burden on the liver and kidney, which is not conducive to the treatment of the disease, but increases the risk of liver and kidney failure. Therefore, when taking metformin, pay attention to monitoring the liver and kidney. functional situation.

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