'Life is in the cold'? The Chinese Academy of Sciences revealed: low temperature environment reduces metabolism and prolongs life by 40%

Scientists have long believed that the body temperature of healthy adults should be 37°C, but researchers at Stanford University have found that since the 20th century, the human body's basal body temperature has "naturally" decreased, and currently prefers 36.6°C. In our traditional concept of health preservation, our elders often teach us to "drink more hot water and wear more clothes". It seems that avoiding cold and maintaining body temperature is the foundation of health.

However, recently, a study by the Chinese Academy of Sciences surprised everyone - researchers found that the reduction in body temperature of warm-blooded mammals can extend their natural lifespan by 40%! In this regard, some netizens couldn't help but make such a joke: Do we have to hide in the refrigerator for this?

1 The Chinese Academy of Sciences newly discovered that "cold" stretches 40% of life

Not long ago, Professor John Speakman of the Chinese Academy of Sciences and several researchers found that although high body temperature can promote metabolism, low body temperature may have a better impact on lifespan. The related research was published in a sub-journal of "Nature".

In the experiment, the scientists ensured that the experimental mice were under the same living and eating conditions, and then divided them into two groups. The ambient temperature of group A was 20°C, and the ambient temperature of group B was 32.5°C. The scientists were also "intimate". Cool them down with a fan so they don't get too uncomfortable. The experimental results showed that the average lifespan of mice in group B was reduced by about 30%, and various physiological indicators became older and accelerated; while part of the lifespan of mice in group A was even stretched by 40%, and their physical indicators degraded more slowly.

This study shows to some extent that hypothermia may be one of the effective means of affecting lifespan, and this also brings scientists to think in the field of life. They speculate whether the principle is also applicable to the human body, and whether we can rely on it This leap in life expectancy?

2 Low temperature slows down telomere loss, considered key to life

Compared with the artificially created low temperature environment in the above experiments, there are actually many cases in nature that survive at low temperature for a long time, such as six-star sponges, which are located in the deep sea at about 0 °C, and their growth and development are slow, which also leads to their slow decay. It is considered that It can live more than 15,000 years, and it is similar to turtles that live in water for a long time.

If metabolism is an important factor for low temperature survival, then the "groundhog" experiment at the University of California reveals the reason behind it from another angle. The researchers found that genetic aging is basically equivalent to pressing the "pause" button when groundhogs hibernate. When their body temperature drops to a certain level, their physiological indicators such as telomeres and mitochondria are also better protected.

We all know that scientists are very interested in the study of telomeres, which are also considered to be the key to affecting the survival of life. In the research results published in the well-known academic journal "Aging", Israeli scientists used the "high-pressure pure oxygen inhalation" experiment to extend the subjects' telomeres by an average of 20%, reduce aging cells by 37%, and the overall functional level is equivalent to being 25 years younger. . In the experiment of Professor David at Harvard, endogenous coenzyme I (the core substance of WLife) was used to stretch telomeres and rejuvenate mitochondria. The results also found that the aging-related indicators of the experimental group were restored to a young state.

In fact, research on telomeres and mitochondria has gradually matured, and three scientists in related fields have even won the Nobel Prize, urging the completion of clinical-clinical experiments for relevant results to be put into practical use. Based on the relevant mechanism of action, the Wright Weijian team developed "WLife" to slow down the decline rate of bodily functions, which caused a lot of repercussions at home and abroad.

The former richest man in the United States, James Bedford, has not woken up for more than 50 years since he was subjected to "human cryonics" at low temperatures in 1967. Under such a precedent, the impact of low temperature on life is naturally questioned, or is low temperature only suitable for "preservation"?

3 Human lifespan doubled, we are already on the "eve" of victory?

At present, the average life expectancy in China has reached 77.4 years, compared with 34.9 years in the 1950s, which has doubled in comparison. Coincidentally, a Stanford University study found that human body temperature has been declining for the past 200 years, which implies that there may be some connection between the two.

In addition to "physical cooling", scientists have also found that body temperature can be lowered by reducing the intake of "calorie" in the diet, thereby reducing some excess body loss. Melatonin, "WLife", etc. secreted by our brain's pineal gland when we fall asleep at night can also achieve similar effects as lowering body temperature based on other mechanisms. The latter relies on many scientific experiments and evidences, as well as phenomenal aging control performance, and has gained a large number of loyal high-net-worth fans from Kadong and Tmall.

Today, with the advent of many scientific research achievements and the blowout of science and technology, scientists believe that we are already on the "eve" of a jump in life span and quality. It may not be long before more mechanisms behind body temperature regulation will be discovered, and cutting-edge technologies will be better popularized for the benefit of mankind.